BMD {epicalc}R Documentation

Bone Mineral Density in Postmenopausal Women

Description

This data contains information from a clinical trial investigating three doses of a drug which is thought to affect bone mineral density levels in postmenopausal women. Treatment 1 is the lowest dosage of the drug and Treatment 3 is the highest. Subjects were postmenopausal women who were randomly allocated to one to the three doses. Bone mineral densities were measured at the start of the trial and at 12 and 24 mnths after the trial commenced.

Usage

data(BMD)

Format

A data frame with 1,439 observations on the following 9 variables.

subj

Subject ID

month

Months since start of trial (0, 12, 24)

group

Treatment group (1, 2, 3)

bmd

Bone mineral density at hip (g/cm^2)

smoking

Smoking status (1=No, 2=Yes (<10 per day), 3=10+ per day)

hrt

Yes or No

bmi

Body mass index (kg/m^2)

yrs

Number of years since menopause

age

Age at start of trial

Source

Nand SL, Wren BG, Gross B, Heller GZ (1999). Bone Density Effects of Continuous Estrone Sulfate and Varying Doses of Medroxyprogesterone Acetate, Obstetrics and Gynecology, 93(6), 1009-1013.

Examples

data(BMD)
use(BMD)
des()
aggregate.plot(bmd, month, group)
boxplot(bmd~month:group, col=5:7, xaxt="n", las=1)

[Package epicalc version 3.5.1.8 Index]